The Gastroenterology Teaching Project

Mucosal Digestion and Absorptive Function

UTP 6

Table of Contents

  1. Amplification of surface area of human small intestine
  2. Villus-crypt distribution of cell function
  3. Intestinal membrane glycoprotein synthesis
  4. Synthesis and processing of sucrase-isomaltase
  5. Intestinal glycoprotein degradation
  6. Functional comparison small and large intestine
  7. Multiple digestive-absorptive processes in the small intestine
  8. Major areas of absorption of nutrients after a meal
  9. Mechanisms of transport: passive diffusion
  10. Mechanisms of transport: carrier-mediated (facilitated diffusion)
  11. Mechanisms of transport: active transport of glucose is Na dependent
  12. Digestive enzymes act at different sites
  13. Intraluminal starch digestion
  14. Disaccharide digestion precedes monosaccharide absorption
  15. Different modes of carbohydrate digestion-absorption
  16. Preferred structure for active transport of monosaccharide
  17. Dietary fiber
  18. Surface digestion provides absorptive advantage for glucose
  19. Lactase activity is rate limiting in lactose digestion-absorption
  20. Distribution of disaccharides along intestine in normal subjects
  21. Fasting alters mucosal disaccharides activity
  22. Diet affects mucosal enzyme activity: "Adaption"
  23. Physiologic basis of lactose tolerance test
  24. Interpretations of lactose tolerance test
  25. Factors influencing occurence of symptoms with lactase deficiency
  26. Several factors determinig symptoms in lactose intolerance
  27. Consequences of low intestinal lactase levels
  28. Examples of defects in carbohydrate digestion and absorption
  29. Glucose-galactose malabsorption: a selective monosaccharide absorptive defect
  30. Variety of digestive-absorptive processes for protein
  31. Multiplicity of digestion-absorption pathways ensures adequate protein absorption
  32. Initial steps in protein-digestive absorption
  33. Aminooligopeptidase is the major brush border peptidase
  34. Preferred structure for active amino acid transport
  35. Enhanced amino acid absorption from some dipeptides
  36. Defect in absorption of basic amino acids occur in Cystinuria
  37. Defect in absorption of neural amino acids occur in Hartnup Disease
  38. Peptide absorption is intact in Hartnup Disease
  39. Selective amino acid transport defects occur in Hartnup Disease and Cystinuria
  40. Intestinal digestive-absorptive functions are not equally susceptible to mucosal injury
  41. Effects of injury on digestive absorptive function are not uniform
  42. Villous hypertrophy and increased transport occur following intestinal resection
  43. Luminal nutrients preserve small bowel mass
  44. Small intestinal cell protein is spared during protein starvation
  45. Luminal nutrients required to induce "Adaptation" following intestinal resection
  46. Gastric surgery can result in reactive hypoglycemia
  47. Factors affecting plasma glucose levels after oral ingestion
  48. Fate of D-xylose in the body
  49. Alterations in urinary D-xylose excretion in disease
  50. D-xylose test helpful in distinguishing maldigestion form malabsorption
  51. Consequences of intestinal resection reflect organ function

 
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