Table of Contents
- Amplification of surface area of human small intestine
- Villus-crypt distribution of cell function
- Intestinal membrane glycoprotein synthesis
- Synthesis and processing of sucrase-isomaltase
- Intestinal glycoprotein degradation
- Functional comparison small and large intestine
- Multiple digestive-absorptive processes in the small intestine
- Major areas of absorption of nutrients after a meal
- Mechanisms of transport: passive diffusion
- Mechanisms of transport: carrier-mediated (facilitated diffusion)
- Mechanisms of transport: active transport of glucose is Na dependent
- Digestive enzymes act at different sites
- Intraluminal starch digestion
- Disaccharide digestion precedes monosaccharide absorption
- Different modes of carbohydrate digestion-absorption
- Preferred structure for active transport of monosaccharide
- Dietary fiber
- Surface digestion provides absorptive advantage for glucose
- Lactase activity is rate limiting in lactose digestion-absorption
- Distribution of disaccharides along intestine in normal subjects
- Fasting alters mucosal disaccharides activity
- Diet affects mucosal enzyme activity: "Adaption"
- Physiologic basis of lactose tolerance test
- Interpretations of lactose tolerance test
- Factors influencing occurence of symptoms with lactase deficiency
- Several factors determinig symptoms in lactose intolerance
- Consequences of low intestinal lactase levels
- Examples of defects in carbohydrate digestion and absorption
- Glucose-galactose malabsorption: a selective monosaccharide absorptive
defect
- Variety of digestive-absorptive processes for protein
- Multiplicity of digestion-absorption pathways ensures adequate protein
absorption
- Initial steps in protein-digestive absorption
- Aminooligopeptidase is the major brush border peptidase
- Preferred structure for active amino acid transport
- Enhanced amino acid absorption from some dipeptides
- Defect in absorption of basic amino acids occur in Cystinuria
- Defect in absorption of neural amino acids occur in Hartnup Disease
- Peptide absorption is intact in Hartnup Disease
- Selective amino acid transport defects occur in Hartnup Disease and
Cystinuria
- Intestinal digestive-absorptive functions are not equally susceptible
to mucosal injury
- Effects of injury on digestive absorptive function are not uniform
- Villous hypertrophy and increased transport occur following intestinal
resection
- Luminal nutrients preserve small bowel mass
- Small intestinal cell protein is spared during protein starvation
- Luminal nutrients required to induce "Adaptation" following
intestinal resection
- Gastric surgery can result in reactive hypoglycemia
- Factors affecting plasma glucose levels after oral ingestion
- Fate of D-xylose in the body
- Alterations in urinary D-xylose excretion in disease
- D-xylose test helpful in distinguishing maldigestion form malabsorption
- Consequences of intestinal resection reflect organ function
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